Nearby Anesthetics An area anesthetic, most often lidocaine, is often injected into the knee. Lidocaine has numbing and anti-inflammatory results which will lessen the depth of pain alerts. Recent investigate indicates that effects can past for 3 months or more. One more indicator: Osteoarthritis tends to show up in one joint https://www.theorthopaedicandpainpractice.com/understanding-and-treating-elderly-knee-pain/