There is a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors inside the dorsal horn to minimize afferent discomfort transmission and produce analgesia. Hence, medicines like clonidine that target alpha-two receptors can affect the transmission of ache. Jun 10, 2024 · If clonidine therapy https://www.proleviate.com/post/the-new-pain-killer-conolidine