Even though fewer typical, by far the most severe Uncomfortable side effects of ursodiol are described underneath, along with what to do if they occur. Nonabsorbed ursodiol passes to the colon where it is usually 7-dehydroxylated to lithocholic acid. Some ursodiol is epimerized to chenodiol (CDCA) through a 7-oxo https://www.youtube.com/watch?v=A07qHOeWON8